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Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy

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Trial Profile

Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy

Status: Active, no longer recruiting
Phase of Trial: Phase 0

Latest Information Update: 13 Oct 2025

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At a glance

Most Recent Events

  • 26 Sep 2025 Status changed from recruiting to active, no longer recruiting.
  • 27 Jan 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Dec 2025.
  • 29 Sep 2023 Number of treatment arms have been increased from 1 to 2 by the addition of Experimental: Monogenetic Epileptic Encephalopathy arm comprising 30 more children. Inclusion criteria is updated to decrease the minimum age limit from 2 months to 0 months. Timelines for all the primary end-points have been modified.

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