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A Phase I/II First-In-Human Clinical Trial to Evaluate the Safety, Tolerability and Anti-Tumor Activity of IMA402, a Bispecific TCER Targeting PRAME, in Patients With Recurrent and/or Refractory Solid Tumors

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Trial Profile

A Phase I/II First-In-Human Clinical Trial to Evaluate the Safety, Tolerability and Anti-Tumor Activity of IMA402, a Bispecific TCER Targeting PRAME, in Patients With Recurrent and/or Refractory Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 29 Aug 2024

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At a glance

  • Drugs IMA 402 (Primary)
  • Indications Lung cancer; Ovarian cancer; Skin cancer; Solid tumours; Synovial sarcoma; Uterine cancer; Uveal melanoma
  • Focus Adverse reactions; First in man; Proof of concept; Therapeutic Use
  • Sponsors Immatics N.V.

    • Most Recent Events

    • 21 Mar 2024 According to an Immatics N.V. media release, first clinical data in at least 15 patients in dose escalation across multiple solid cancers, but initially focused on melanoma, is anticipated to be announced in 2H 2024.
    • 14 Nov 2023 According to an Immatics N.V. media release, first patient has been dosed.
    • 10 Aug 2023 According to an Immatics N.V. media release, patient enrollment for IMA402 Phase 1/2 trial underway, first data expected in 2024

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