Trial Profile

4CAST: A Phase 1b Dose Exploration and Dose Expansion, Open-label, Single-centre Study Evaluating the Safety and Efficacy of INO-464 in Combination With Chemotherapy in Patients With metASTatic Breast Cancer

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 23 May 2025

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At a glance

Drugs Dexamethasone (Primary) ; Docetaxel (Primary) ; Seviteronel (Primary)
Indications Advanced breast cancer; Male breast cancer; Triple negative breast cancer
Focus Adverse reactions
Acronyms 4CAST

15 May 2025 Planned End Date changed from 1 Dec 2024 to 1 Dec 2027.
15 May 2025 Planned primary completion date changed from 1 Jul 2024 to 1 Jul 2026.
04 Jun 2024 Results presented at the 60th Annual Meeting of the American Society of Clinical Oncology

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