Trial Profile

Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 24 Apr 2026

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At a glance

Drugs Actinium 225 rosopatamab (Primary) ; Pembrolizumab (Primary) ; Apalutamide; Darolutamide; Enzalutamide
Indications Adenocarcinoma; Prostate cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

21 Apr 2026 Planned number of patients changed from 76 to 52.
21 Apr 2026 Status changed from active, no longer recruiting to recruiting.
03 Feb 2026 Status changed from recruiting to active, no longer recruiting.

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