Trial Profile

A Phase 2, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of Sotatercept Versus Placebo for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension (Cpc-PH) Due to Heart Failure With Preserved Ejection Fraction (HFpEF)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 08 Dec 2025

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At a glance

18 Nov 2025 According to a Merck and Co media release, the company is planning to present these results at a future scientific congress and intends to proceed with Phase 3 development.
18 Nov 2025 According to a Merck and Co media release, Primary endpoint (Change From Baseline in Pulmonary Vascular Resistance (PVR) at Week 24) has been met.
18 Nov 2025 Results presented in the Merck and Co Media Release

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