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Dose response and safety of an oral PCSK9i, NNC0385-0434, in patients with established atherosclerotic cardiovascular disease (ASCVD) or ASCVD risk on maximally tolerated statin dose and other lipid-lowering therapy requiring further LDL-C reduction

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Dose response and safety of an oral PCSK9i, NNC0385-0434, in patients with established atherosclerotic cardiovascular disease (ASCVD) or ASCVD risk on maximally tolerated statin dose and other lipid-lowering therapy requiring further LDL-C reduction

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 May 2024

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At a glance

  • Drugs NNC0385 0434 (Primary) ; Evolocumab
  • Indications Atherosclerosis; Cardiovascular disorders; Hypercholesterolaemia
  • Focus Therapeutic Use
  • Sponsors Novo Nordisk

    • Most Recent Events

    • 19 Jul 2022 Status changed from active, no longer recruiting to completed.
    • 07 Jul 2022 This trial has been completed in Germany (End Date: 20 Jun 2022), according to European Clinical Trials Database record.
    • 21 Mar 2022 Status changed from recruiting to active, no longer recruiting.

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