Trial Profile

Phase 1/2 Modular Dose Escalation With Cohort Expansion of CP-506 (HAP) in Patients With Solid Tumor Types With High Incidence of HRD/FAD in Monotherapy or With Carboplatin or Patients With Solid Tumour and OPD Receiving ICI

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 15 Oct 2025

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At a glance

Drugs Atezolizumab (Primary) ; Avelumab (Primary) ; Carboplatin (Primary) ; Cemiplimab (Primary) ; CP-506 (Primary) ; Durvalumab (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary) ; Pembrolizumab (Primary)
Indications Advanced breast cancer; Head and neck cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Solid tumours
Focus Adverse reactions; First in man

07 Oct 2025 Planned End Date changed from 1 May 2026 to 1 May 2027.
07 Oct 2025 Planned primary completion date changed from 1 Feb 2026 to 1 Feb 2027.
27 Apr 2023 Status changed from not yet recruiting to recruiting.

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