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A Phase 2, Randomized, Double-blind, Multi-dose, Dose Finding Study to Evaluate the Safety, Tolerability and Immunogenicity of AFX3772 Compared With PCVs in Healthy Infants

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Trial Profile

A Phase 2, Randomized, Double-blind, Multi-dose, Dose Finding Study to Evaluate the Safety, Tolerability and Immunogenicity of AFX3772 Compared With PCVs in Healthy Infants

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Oct 2025

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At a glance

  • Drugs AFX 3772 (Primary) ; Pneumococcal 13-valent CRM197 vaccine conjugate
  • Indications Pneumococcal infections
  • Focus Adverse reactions
  • Sponsors GSK

Most Recent Events

  • 21 Oct 2025 Number of treatment arms are increased from 5 to 7 by the addition of Experimental: Part 2 Group 6 and Active Comparator: Part 2 Group 7 arms.
  • 21 Oct 2025 Status changed from active, no longer recruiting to completed.
  • 02 Dec 2024 Planned number of patients changed from 121 to 472.

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