Trial Profile

A Randomized, Phase 3, Open-label Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Pembrolizumab Versus Intravenous Pembrolizumab, Administered With Platinum Doublet Chemotherapy, in the First-Line Treatment of Participants With Metastatic Squamous or Nonsquamous Non-Small-Cell Lung Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 11 Sep 2026

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At a glance

Drugs Pembrolizumab (Primary) ; Carboplatin; Cisplatin; Paclitaxel; Pembrolizumab; Pemetrexed
Indications Non-small cell lung cancer
Focus Pharmacokinetics; Registrational
Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.

10 Apr 2026 Planned number of patients changed from 512 to 531.
27 Mar 2025 According to a Merck media release, data from time and motion study presented at the European Lung Cancer Congress (ELCC) 2025.
27 Mar 2025 Results published in the Media Release

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