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A Phase 1b Multi-Center, Open-Label, Dose-Escalation, Prime And Boost Vaccination Evaluation of VRON-0200 Using Two Chimpanzee Adenoviral Vectors in Adult Participants With Chronic HBV Infection Who Are Currently Receiving HBV Nucleos(t)Ide Reverse Transcriptase Inhibitors

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Trial Profile

A Phase 1b Multi-Center, Open-Label, Dose-Escalation, Prime And Boost Vaccination Evaluation of VRON-0200 Using Two Chimpanzee Adenoviral Vectors in Adult Participants With Chronic HBV Infection Who Are Currently Receiving HBV Nucleos(t)Ide Reverse Transcriptase Inhibitors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Nov 2024

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At a glance

  • Drugs Elebsiran (Primary) ; VRON-0200 (Primary) ; Tobevibart
  • Indications Hepatitis B
  • Focus Adverse reactions; First in man
  • Sponsors Virion Therapeutics
  • Most Recent Events

    • 19 Nov 2024 According to a Virion Therapeutics media release, dose escalation Cohort 1 (low dose) and Cohort 2 (high dose) is enrolled and Cohort 3 is enrolling patients. Additionally company look forward to sharing more results in early 2025.
    • 19 Nov 2024 According to a Virion Therapeutics media release, data from this study published as a late breaker poster presentation at The Liver Meeting 2024 (The American Association for the Study of the Liver), in San Diego, California, US.
    • 19 Nov 2024 Results presented in the Virion Therapeutics Media Release.

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