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A Study to Evaluate the Safety and Immune Activity of PeptiCRAd-1 in Combination With Pembrolizumab in Patients With Injectable Solid Tumors in Indications Known to Express NY-ESO-1 and MAGE-A3

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Trial Profile

A Study to Evaluate the Safety and Immune Activity of PeptiCRAd-1 in Combination With Pembrolizumab in Patients With Injectable Solid Tumors in Indications Known to Express NY-ESO-1 and MAGE-A3

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 16 Jan 2024

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At a glance

  • Drugs Pembrolizumab (Primary) ; VALO-D102 (Primary) ; Cyclophosphamide
  • Indications Advanced breast cancer; Male breast cancer; Malignant melanoma; Myxoid liposarcoma; Non-small cell lung cancer; Sarcoma; Synovial sarcoma; Triple negative breast cancer
  • Focus Adverse reactions; First in man
  • Acronyms START
  • Sponsors Valo Therapeutics

    • Most Recent Events

    • 08 Jan 2024 Planned End Date changed from 1 Jan 2024 to 1 Sep 2025.
    • 08 Jan 2024 Planned primary completion date changed from 1 Oct 2023 to 1 Jun 2025.
    • 29 Nov 2023 According to a Valo therapeutics media release, the company received approval from Germany's PEI (Paul Ehrlich Institute) to extend the tumor types to be treated into two subtypes of sarcoma, synovial and myxoid round cell sarcoma. Third recruitment center has been opened recently in Tubingen.

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