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A Randomized, Double-Blind, Placebo-Controlled Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects With Gout and Mild to Moderate Chronic Kidney Disease

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects With Gout and Mild to Moderate Chronic Kidney Disease

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 01 Jul 2024

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At a glance

  • Drugs ALLN 346 (Primary)
  • Indications Gout; Hyperuricaemia; Renal failure
  • Focus Adverse reactions; Proof of concept
  • Acronyms Study 202
  • Sponsors Allena Pharmaceuticals
  • Most Recent Events

    • 04 Jun 2024 Results of post hoc( (Study 202) and (Study 102) ) explaining Association between clinical and disease characteristics and detectable or undetectable baseline ctDNA in patients with metastatic uveal melanoma, presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 21 Jun 2023 Status changed from recruiting to discontinued.
    • 19 Jul 2022 According to an Allena Pharmaceuticals media release, enrollment of the first two cohorts in gout patients with stage 2 (cohort A) and stage 3 (cohort B) chronic kidney disease (CKD) has been completed. topline safety and efficacy data from cohort A and cohort B are expected to be available later this quarter.
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