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Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

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Trial Profile

Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Nov 2024

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At a glance

  • Drugs EP 547 (Primary)
  • Indications Pruritus
  • Focus Proof of concept; Therapeutic Use
  • Acronyms PACIFIC
  • Sponsors Escient Pharmaceuticals

    • Most Recent Events

    • 18 Nov 2024 According to an Incyte Pharmaceuticals media release, data from the Phase 2 study evaluating MRGPRX4 (INCB000547) in cholestatic pruritus (CP) does not support further development.
    • 14 Oct 2024 Status changed from active, no longer recruiting to completed.
    • 13 May 2024 Status changed from recruiting to active, no longer recruiting.

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