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The efficacy and safety of perioperative PD-1 antibody combined with concurrent chemoradiotherapy in the treatment of locally advanced gastric cancer

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Trial Profile

The efficacy and safety of perioperative PD-1 antibody combined with concurrent chemoradiotherapy in the treatment of locally advanced gastric cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Dec 2023

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At a glance

  • Drugs Gimeracil/oteracil/tegafur (Primary) ; Paclitaxel (Primary) ; Sintilimab (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use
  • Acronyms SHARED

    • Most Recent Events

    • 24 Oct 2023 Primary endpoint (To evaluate the pathologic complete response rate of locally advanced gastric cancer treated with concurrent chemoradiotherapy with PD-1 antibody.) has been met.
    • 24 Oct 2023 Results presented at the 48th European Society for Medical Oncology Congress
    • 13 Apr 2022 Results assessing the microenvironment of immune cell infiltration at baseline and post-treatment of the patients in SHARED trial presented at the 113th Annual Meeting of the American Association for Cancer Research

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