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An Open-label, Fixed-sequence Study to Assess the Effect of Repeated Doses of Capivasertib on the Pharmacokinetics of Oral Midazolam (a CYP450 3A Probe) in Patients With Advanced Solid Tumours

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Trial Profile

An Open-label, Fixed-sequence Study to Assess the Effect of Repeated Doses of Capivasertib on the Pharmacokinetics of Oral Midazolam (a CYP450 3A Probe) in Patients With Advanced Solid Tumours

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 31 Jan 2024

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At a glance

  • Drugs Capivasertib (Primary) ; Midazolam (Primary)
  • Indications Solid tumours
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 06 Mar 2023 Status changed from active, no longer recruiting to completed.
    • 17 Oct 2022 Status changed from recruiting to active, no longer recruiting.
    • 16 May 2022 Planned number of patients changed from 23 to 29.

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