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A Phase III, Multicenter, Single-Arm Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Pediatric Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

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Trial Profile

A Phase III, Multicenter, Single-Arm Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Pediatric Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 12 Jun 2025

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At a glance

  • Drugs Crovalimab (Primary) ; Crovalimab (Primary)
  • Indications Atypical Haemolytic Uraemic Syndrome
  • Focus Registrational; Therapeutic Use
  • Acronyms COMMUTE-p
  • Sponsors Roche

Most Recent Events

  • 06 Jun 2025 Planned End Date changed from 20 Sep 2029 to 2 Dec 2029.
  • 06 Jun 2025 Planned primary completion date changed from 12 Dec 2025 to 5 Jul 2025.
  • 04 May 2025 Status changed from recruiting to active, no longer recruiting.

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