A Phase 1b, Open Label, Dose Escalation Study of IOA-289, an Orally Bioavailable, Selective Autotaxin (ENPP2) Inhibitor Alone and in Combination with Gemcitabine/nab-paclitaxel in Patients with Metastatic Pancreatic Cancer
Latest Information Update: 24 Mar 2025
At a glance
- Drugs Gemcitabine (Primary) ; IOA 289 (Primary) ; Paclitaxel (Primary)
- Indications Adenocarcinoma; Pancreatic cancer; Pancreatic ductal carcinoma
- Focus Adverse reactions
- Acronyms AION-01
- Sponsors iOnctura
Most Recent Events
- 20 Mar 2025 Planned End Date changed from 1 Feb 2025 to 1 Mar 2026.
- 20 Mar 2025 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2025.
- 20 Mar 2025 Status changed from recruiting to active, no longer recruiting.