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A retrospective cohort study to determine association of receipt of Pfizer-BNT162b2 mRNA or Moderna mRNA-1273 vaccines in patients with cirrhosis compared at risk of infection and severe disease from COVID-19

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Trial Profile

A retrospective cohort study to determine association of receipt of Pfizer-BNT162b2 mRNA or Moderna mRNA-1273 vaccines in patients with cirrhosis compared at risk of infection and severe disease from COVID-19

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 20 Jan 2022

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At a glance

  • Drugs Ad26.COV2 S (Primary) ; Elasomeran (Primary) ; Tozinameran (Primary)
  • Indications COVID-19 respiratory infection
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms VOCAL cohort
  • Most Recent Events

    • 12 Jan 2022 Results published in the Hepatology
    • 15 Nov 2021 Results investigating the association of receipt of the Pfizer BNT162b2 mRNA or Moderna 1273 mRNA vaccines in patients with cirrhosis compared to a propensity-matched control group of patients at similar risk of infection and severe disease from COVID-19, presented at The Liver Meeting 2021: 72nd Annual Meeting of the American Association for the Study of Liver Diseases
    • 15 Nov 2021 Results of (n=3242 unvaccinated )and (n=254 vaccinated) patients with cirrhosis, presented at The Liver Meeting 2021: 72nd Annual Meeting of the American Association for the Study of Liver Diseases

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