Trial Profile

A Phase II Pilot Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to Chimeric Antigen Receptor T-Cell Therapy (CAR-T) in Hematological Malignancies

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 30 Jan 2025

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At a glance

28 Jan 2025 Planned End Date changed from 31 Dec 2025 to 31 Dec 2027.
28 Jan 2025 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2026.
12 Dec 2023 Results (n=26) examining the changes in neurocognitive performance before and after CAR T cell therapy, presented at the 65th American Society of Hematology Annual Meeting and Exposition

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