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SIGNATURE Study: Post-market, Randomized Controlled, Multicenter, Single Blinded Prospective Trial Investigating the Paclitaxel-Coated Balloon (Legflow DCB) Treatment Versus Uncoated Balloon Angioplasty Treatment for Femoro-popliteal Lesions

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Trial Profile

SIGNATURE Study: Post-market, Randomized Controlled, Multicenter, Single Blinded Prospective Trial Investigating the Paclitaxel-Coated Balloon (Legflow DCB) Treatment Versus Uncoated Balloon Angioplasty Treatment for Femoro-popliteal Lesions

Status: Recruiting
Phase of Trial: Phase IV

Latest Information Update: 15 Feb 2023

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At a glance

  • Drugs Paclitaxel (Primary)
  • Indications Peripheral artery restenosis
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms SIGNATURE

    • Most Recent Events

    • 07 Feb 2023 Planned End Date changed from 1 Sep 2024 to 1 May 2026.
    • 07 Feb 2023 Planned primary completion date changed from 1 Sep 2023 to 1 May 2025.
    • 10 Aug 2022 Planned number of patients changed from 140 to 148.

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