Trial Profile

An Open-label, Phase 1b Study of R289, an IRAK1/4 Inhibitor, in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS) Who Are Relapsed/Refractory/Resistant to Prior Therapies

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 12 May 2025

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At a glance

Drugs R 289 (Primary)
Indications Myelodysplastic syndromes
Focus Adverse reactions
Sponsors Rigel Pharmaceuticals

Most Recent Events

06 May 2025 According to a Rigel Pharmaceuticals media release, enrollment in the sixth dose level (500 mg twice daily) is ongoing.
15 Apr 2025 Planned number of patients changed from 34 to 86.
15 Apr 2025 Planned End Date changed from 1 May 2025 to 1 Dec 2026.

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