Trial Profile

Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Monotherapy in Patients with Symptomatic Generalized Myasthenia Gravis

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 17 Feb 2026

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At a glance

Drugs Cemdisiran (Primary) ; Pozelimab (Primary)
Indications Myasthenia gravis
Focus Registrational; Therapeutic Use
Acronyms NIMBLE
Sponsors Regeneron Pharmaceuticals

Most Recent Events

12 Feb 2026 Actual primary completion date changed from 18 Jul 2025 to 8 Jul 2025.
26 Aug 2025 According to Regeneron Pharmaceuticals media release, detailed results from the NIMBLE trial will be presented at an upcoming medical meeting.
26 Aug 2025 According to Regeneron Pharmaceuticals media release, Primary endpoint has been met. (Change in Myasthenia Gravis-Activities of Daily Living (MG-ADL) total score)

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