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A Phase 1 Study of JNJ-78306358, a T Cell Redirecting Bispecific Antibody Targeting HLA-G for Advanced Stage Solid Tumors

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Trial Profile

A Phase 1 Study of JNJ-78306358, a T Cell Redirecting Bispecific Antibody Targeting HLA-G for Advanced Stage Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 Aug 2024

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At a glance

  • Drugs JNJ-78306358 (Primary)
  • Indications Adenocarcinoma; Carcinoma; Colorectal cancer; Endometrial cancer; Fallopian tube cancer; Lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions
  • Sponsors Janssen Research & Development
  • Most Recent Events

    • 06 Aug 2024 Results assessing the safety, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of JNJ-78306358 in patients with advanced solid tumors were published in the Cancer Immunology Immunotherapy.
    • 24 Oct 2023 Results (n=39) presented at the 48th European Society for Medical Oncology Congress.
    • 23 Feb 2023 Status changed from active, no longer recruiting to completed.

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