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A Phase 1, Open-label Study With Two Independent Parts: Collecting Samples for Metabolites in Safety Testing Analysis of Zibotentan After Repeated Administration (Part 1); and a Randomised, Cross-over, Three Period, Three-treatment, Single Dose Study to Assess the Relative Bioavailability of Different Formulations of Zibotentan and Dapagliflozin (Part 2) in Healthy Adult Participants

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A Phase 1, Open-label Study With Two Independent Parts: Collecting Samples for Metabolites in Safety Testing Analysis of Zibotentan After Repeated Administration (Part 1); and a Randomised, Cross-over, Three Period, Three-treatment, Single Dose Study to Assess the Relative Bioavailability of Different Formulations of Zibotentan and Dapagliflozin (Part 2) in Healthy Adult Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Nov 2021

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At a glance

  • Drugs Dapagliflozin (Primary) ; Zibotentan (Primary)
  • Indications Renal failure
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 22 Nov 2021 Status changed from active, no longer recruiting to completed.
    • 07 Oct 2021 Planned End Date changed from 6 Oct 2021 to 12 Oct 2021.
    • 07 Oct 2021 Planned primary completion date changed from 6 Oct 2021 to 12 Oct 2021.

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