Trial Profile

A Phase 1 Open-Label Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of LP-168 in Adult Patients With Relapse or Refractory B-Cell Lymphoma

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 10 Oct 2025

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At a glance

Drugs Rocbrutinib (Primary)
Indications Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
Focus Adverse reactions; First in man
Sponsors Guangzhou Lupeng Pharmaceutical

23 Sep 2025 Planned End Date changed from 30 Jun 2025 to 30 Jun 2027.
23 Sep 2025 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2026.
07 Oct 2024 Planned End Date changed from 30 Jun 2024 to 30 Jun 2025.

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