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Randomized, single dose, three-way crossover open label study to evaluate the pharmacokinetic parameters of 1000 mg Acetaminophen, 300 mg Ibuprofen and 1 mg/mL Xylometazoline hydrochloride (1 spray into each nostril; 0.138mL per spray), after an administration to 30 healthy adults under fasting conditions.

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Randomized, single dose, three-way crossover open label study to evaluate the pharmacokinetic parameters of 1000 mg Acetaminophen, 300 mg Ibuprofen and 1 mg/mL Xylometazoline hydrochloride (1 spray into each nostril; 0.138mL per spray), after an administration to 30 healthy adults under fasting conditions.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Apr 2022

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At a glance

  • Drugs Ibuprofen/paracetamol (Primary) ; Xylometazoline (Primary) ; Ibuprofen; Paracetamol
  • Indications Fever; Pain; Postoperative pain
  • Focus Pharmacokinetics
  • Sponsors AFT Pharmaceuticals

    • Most Recent Events

    • 04 Apr 2022 Status changed from active, no longer recruiting to completed.
    • 25 Nov 2021 Status changed from recruiting to active, no longer recruiting.
    • 12 Sep 2021 Status changed from not yet recruiting to recruiting.

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