A Phase 1 Open-Label Dose-Escalation Study of the Safety of Adoptively Transferred Autologous CD8+ T Lymphocytes Targeting HPV-16 E6/E7, HPV-18 E6/E7 and Survivin in Patients With Relapsed or Refractory HPV-related Oropharyngeal Cancers
Latest Information Update: 19 Jan 2024
At a glance
- Drugs NEXI 003 (Primary)
- Indications Oropharyngeal cancer; Solid tumours
- Focus Adverse reactions; First in man
- Sponsors NexImmune
Most Recent Events
- 12 Jan 2024 Planned End Date changed from 25 Aug 2025 to 25 Aug 2027.
- 12 Jan 2024 Planned primary completion date changed from 1 Jul 2024 to 1 Jul 2026.
- 12 Jan 2024 Planned initiation date changed from 31 Mar 2023 to 31 Mar 2025.