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A Phase II Single Arm Clinical Trial Assessing the Efficacy and Safety of BIntrafusp Alfa (M7824) in Previously Treated Advanced Malignant Pleural MESothelioma (BIMES)

Trial Profile

A Phase II Single Arm Clinical Trial Assessing the Efficacy and Safety of BIntrafusp Alfa (M7824) in Previously Treated Advanced Malignant Pleural MESothelioma (BIMES)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 May 2025

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At a glance

  • Drugs Bintrafusp alfa (Primary)
  • Indications Malignant-mesothelioma
  • Focus Therapeutic Use
  • Acronyms BIMES

Most Recent Events

  • 01 May 2025 Primary endpoint has not been met. (To evaluate the efficacy of the treatment), according to results published in the Lung Cancer.
  • 01 May 2025 Results assessing the efficacy (progression-free survival [PFS]) of bintrafusp alfa in patients with pleural mesothelioma (PM) who had progressed to platinum-based chemotherapy and had not previously received immunotherapy, published in the Lung Cancer.
  • 19 Sep 2024 Status changed from recruiting to completed.

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