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A Multi-center, Open-label, Phase I/Ib Study to Assess the Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, a Poly (ADP-ribose) Polymerase (PARP) Inhibitor, in Patients With Locally Advanced or Metastatic Solid Tumors

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Trial Profile

A Multi-center, Open-label, Phase I/Ib Study to Assess the Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, a Poly (ADP-ribose) Polymerase (PARP) Inhibitor, in Patients With Locally Advanced or Metastatic Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Sep 2024

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At a glance

  • Drugs RP 12146 (Primary)
  • Indications Advanced breast cancer; Biliary cancer; Colorectal cancer; Endometrial cancer; Fallopian tube cancer; Gastric cancer; Male breast cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Prostate cancer; Small cell lung cancer; Solid tumours
  • Focus Adverse reactions
  • Sponsors Rhizen Pharmaceuticals
  • Most Recent Events

    • 07 May 2024 Status changed from active, no longer recruiting to completed.
    • 02 Apr 2024 Planned End Date changed from 31 Mar 2024 to 30 Apr 2024.
    • 02 Apr 2024 Planned primary completion date changed from 1 Mar 2024 to 30 Apr 2024.

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