A Phase 2, Multicenter, Randomized, Open-Label Trial of GEN1046 as Monotherapy and in Combination Pembrolizumab Therapy in Subjects With Relapsed/Refractory Metastatic Non-Small Cell Lung Cancer After Treatment With Standard of Care Therapy With an Immune Checkpoint Inhibitor
Latest Information Update: 26 May 2026
At a glance
- Drugs Acasunlimab (Primary) ; Pembrolizumab (Primary)
- Indications Non-small cell lung cancer
- Focus Therapeutic Use
- Sponsors Genmab A/S
Most Recent Events
- 26 May 2026 Planned End Date changed from 27 May 2027 to 30 Aug 2026.
- 29 Dec 2025 Status changed from active, no longer recruiting to discontinued, according to Genmab media release. This decision reflects prioritization of higher impact opportunities across Genmabs late stage pipeline and increasingly competitive landscape.
- 06 Nov 2025 Planned End Date changed from 1 Mar 2027 to 27 May 2027.