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A Phase 1a/b Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Subjects With Solid Malignancies

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Trial Profile

A Phase 1a/b Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Subjects With Solid Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Jul 2024

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At a glance

  • Drugs Docetaxel (Primary) ; GS-9716 (Primary) ; Sacituzumab govitecan (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions
  • Sponsors Gilead Sciences

    • Most Recent Events

    • 29 Aug 2023 Planned End Date changed from 1 May 2028 to 1 Jan 2027.
    • 29 Aug 2023 Planned primary completion date changed from 1 Mar 2027 to 1 Jan 2027.
    • 31 Jul 2023 Number of treatment arms have been reduced from 12 to 6 by the removal of 3 arms from part B and 3 arms from part C. One primary end-point is removed and patient enrollment is reduced. All the specific indication are removed from indications and Gemcitabine is removed from drugs.
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