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Phase I Study of the First-In-Class Agent CPI-613 (Devimistat) in Combination With Modified FOLFIRINOX Plus Bevacizumab in Patients With Metastatic Colorectal Cancer

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Trial Profile

Phase I Study of the First-In-Class Agent CPI-613 (Devimistat) in Combination With Modified FOLFIRINOX Plus Bevacizumab in Patients With Metastatic Colorectal Cancer

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I/II

Latest Information Update: 31 Aug 2023

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At a glance

  • Drugs Devimistat (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Adverse reactions
  • Sponsors Cornerstone Pharmaceuticals Inc
  • Most Recent Events

    • 28 Aug 2023 Status changed from not yet recruiting to withdrawn prior to enrolment.
    • 10 Nov 2022 Planned End Date changed from 1 Jun 2024 to 1 Nov 2024.
    • 10 Nov 2022 Planned primary completion date changed from 1 Dec 2023 to 1 Mar 2024.

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