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A Pivotal Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Efficacy and Safety of DMX-200 in Patients With Focal Segmental Glomerulosclerosis (FSGS) Who Are Receiving an Angiotensin II Receptor Blocker (ARB)

Trial Profile

A Pivotal Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Efficacy and Safety of DMX-200 in Patients With Focal Segmental Glomerulosclerosis (FSGS) Who Are Receiving an Angiotensin II Receptor Blocker (ARB)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 14 Aug 2025

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At a glance

  • Drugs Irbesartan/propagermanium (Primary)
  • Indications Focal segmental glomerulosclerosis
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms ACTION3
  • Sponsors Dimerix Bioscience

Most Recent Events

  • 31 Jul 2025 According to an Amicus Therapeutics media release, this trial is being funded and executed by Dimerix, is on track for full enrollment by end of the year.
  • 01 Jul 2025 Planned End Date changed from 1 Jun 2026 to 1 Dec 2029.
  • 01 Jul 2025 Planned primary completion date changed from 1 Jun 2024 to 1 Dec 2029.

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