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A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Entospletinib in Combination With Intensive Induction and Consolidation Chemotherapy in Adults With Newly Diagnosed Nucleophosmin 1-mutated Acute Myeloid Leukemia

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Trial Profile

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Entospletinib in Combination With Intensive Induction and Consolidation Chemotherapy in Adults With Newly Diagnosed Nucleophosmin 1-mutated Acute Myeloid Leukemia

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 12 Mar 2024

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At a glance

  • Drugs Entospletinib (Primary) ; Cytarabine; Daunorubicin; Idarubicin
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Registrational; Therapeutic Use
  • Acronyms AGILITY
  • Sponsors Kronos Bio

    • Most Recent Events

    • 05 Mar 2024 According to Becton, Dickinson and Company media release, first Patient Enrollment in AGILITY Study has begun.
    • 20 Feb 2023 Planned End Date changed from 1 Jun 2023 to 1 Apr 2023.
    • 20 Feb 2023 Planned primary completion date changed from 1 Jun 2023 to 1 Apr 2023.

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