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A Phase 1a/1b, Multicenter, Open-Label, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Pharmacokinetics, and Anti-tumour Activity of AK127 in Combination With AK104 in Subjects With Advanced or Metastatic Solid Tumours

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Trial Profile

A Phase 1a/1b, Multicenter, Open-Label, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Pharmacokinetics, and Anti-tumour Activity of AK127 in Combination With AK104 in Subjects With Advanced or Metastatic Solid Tumours

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 27 Mar 2024

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At a glance

  • Drugs AK 127 (Primary) ; Cadonilimab (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Akeso Biopharma
  • Most Recent Events

    • 05 Jan 2023 Planned End Date changed from 1 May 2023 to 7 Apr 2025.
    • 05 Jan 2023 Planned primary completion date changed from 1 Mar 2023 to 10 Jan 2025.
    • 21 Oct 2021 Status changed from not yet recruiting to recruiting according to Akeso Biopharma media release

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