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A Phase III Multicenter, Randomized, Double-blind, Double-dummy Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

Trial Profile

A Phase III Multicenter, Randomized, Double-blind, Double-dummy Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 23 Mar 2026

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At a glance

  • Drugs Ocrelizumab (Primary) ; Fingolimod
  • Indications Multiple sclerosis
  • Focus Registrational; Therapeutic Use
  • Acronyms Operetta 2
  • Sponsors Roche

Most Recent Events

  • 23 Mar 2026 Actual primary completion date changed from 9 Jun 2025 to 19 May 2022.
  • 23 Mar 2026 Last checked against ClinicalTrials.gov record.
  • 24 Sep 2025 According to a Genentech media release, data from this study will be presented as on oral presentation at the at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Barcelona, Spain (September 24-26 )

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