A Phase I/II Open Label, Single Center, Study of the Combination of ALX148, Rituximab and Lenalidomide in Patients With Indolent and Aggressive B-Cell Non-Hodgkin Lymphoma
Latest Information Update: 16 Dec 2025
At a glance
- Drugs Evorpacept (Primary) ; Lenalidomide (Primary) ; Rituximab (Primary)
- Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Richter's syndrome
- Focus Adverse reactions; Therapeutic Use
Most Recent Events
- 06 Dec 2025 Primary endpoint (Complete remission (CR) rate (Phase II)) has been met. as per ALX Oncology media release.
- 06 Dec 2025 According to a ALX Oncology media release,data from this trial is being presented Sunday, December 7 during a poster presentation at the American Society of Hematology (ASH) Annual Meeting 2025 in Orlando, Florida.
- 08 May 2025 According to a ALX Oncology media release, the Phase 2 portion of the trial in patients with previously untreated indolent NHL has completed enrollment.