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A Phase 1b, Multicenter, Open Label Study to Evaluate the Safety, Pharmacokinetics and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant

Trial Profile

A Phase 1b, Multicenter, Open Label Study to Evaluate the Safety, Pharmacokinetics and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 01 Jul 2026

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At a glance

  • Drugs Tegoprubart (Primary) ; Antithymocyte globulin; Mycophenolate mofetil; Steroids
  • Indications Renal transplant rejection
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Eledon Pharmaceuticals

Most Recent Events

  • 22 Jun 2026 According to an Eledon Pharmaceuticals media release, in the phase 1b study, long-term data were available for 16 patients, with eight patients followed through 24 months and the longest-followed ongoing patient remaining on tegoprubart for approximately 3.5 years.
  • 23 Jan 2026 Results presented in the Eledon Pharmaceuticals media release.
  • 08 Jan 2026 According to an Eledon Pharmaceuticals media release, long-term data from the Phase 1 and Phase 2 BESTOW studies evaluating tegoprubart in kidney transplantation is anticipated to be reported in 2026.

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