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A Phase 1 First in Human Study Evaluating Safety, Pharmacokinetics and Efficacy of ABBV-400 as Monotherapy and in Combination With Bevacizumab in Adult Subjects With Advanced Solid Tumors

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Trial Profile

A Phase 1 First in Human Study Evaluating Safety, Pharmacokinetics and Efficacy of ABBV-400 as Monotherapy and in Combination With Bevacizumab in Adult Subjects With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Nov 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Telisotuzumab adizutecan (Primary)
  • Indications Acral lentiginous melanoma; Adenocarcinoma; Advanced breast cancer; Cholangiocarcinoma; Colorectal cancer; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Solid tumours; Squamous cell cancer; Uterine cancer
  • Focus First in man; Therapeutic Use
  • Sponsors AbbVie

    • Most Recent Events

    • 30 Oct 2024 According to an AbbVie media release, new safety and efficacy data in pre-treated patients from this trial presented at the European Society for Medical Oncology (ESMO) Congress 2024.
    • 09 Sep 2024 According to an AbbVie Media Release, additional efficacy and safety data from this study will be presented at the upcoming European Society for Medical Oncology (ESMO) Congress 2024 (September 13-17, 2024).
    • 09 Sep 2024 Results presented in an AbbVie Media Release.

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