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Phase I/II Study to Evaluate the Safety and Clinical Efficacy of Atezolizumab (Anti-PD-L1) in Combination With Cabozantinib in Patients With Recurrent Glioblastoma (rGBM)

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Trial Profile

Phase I/II Study to Evaluate the Safety and Clinical Efficacy of Atezolizumab (Anti-PD-L1) in Combination With Cabozantinib in Patients With Recurrent Glioblastoma (rGBM)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 14 Jan 2026

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At a glance

  • Drugs Atezolizumab (Primary) ; Cabozantinib (Primary)
  • Indications Glioblastoma; Glioma; Gliosarcoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 19 Dec 2025 Planned End Date changed from 31 Dec 2025 to 31 Dec 2027.
  • 19 Dec 2025 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2027.
  • 23 Aug 2023 Planned End Date changed from 15 Feb 2024 to 31 Dec 2025.

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