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A Randomised, Double-blinded Phase II Study of Gemcitabine and Nab-Paclitaxel With LSTA1 (Certepetide) or Placebo in Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinoma

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Trial Profile

A Randomised, Double-blinded Phase II Study of Gemcitabine and Nab-Paclitaxel With LSTA1 (Certepetide) or Placebo in Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Jul 2025

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At a glance

  • Drugs Cerepetide (Primary) ; Gemcitabine (Primary) ; Paclitaxel (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer; Pancreatic ductal carcinoma
  • Focus Therapeutic Use
  • Acronyms ASCEND

Most Recent Events

  • 26 Jun 2025 According to a Lisata Therapeutics media release, positive preliminary Cohort B data from this study will be presented at at the European Society for Medical Oncology (ESMO) Gastrointestinal Cancers Congress in Barcelona, Spain, on 2 July, 2025.
  • 27 Feb 2025 According to a Lisata Therapeutics media release, the exact timing of final results from both cohorts will be dependent on accumulating the requisite number of endpoint events in Cohort B and is not something that can be accurately predicted.
  • 27 Feb 2025 According to a Lisata Therapeutics media release, data from 63 patients receiving two IV doses of certepetide 3.2 mg/kg or placebo administered 4 hours apart in combination with SoC, is expected in the coming months.

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