Trial Profile

A Phase 2 Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of KER-050 as Monotherapy or in Combination With Ruxolitinib in Participants With Myelofibrosis

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 02 Apr 2026

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At a glance

Drugs Elritercept (Primary) ; Ruxolitinib (Primary)
Indications Anaemia; Cytopenia; Myelofibrosis
Focus Adverse reactions
Acronyms RESTORE
Sponsors Keros Therapeutics

Most Recent Events

04 Nov 2025 Planned number of patients changed from 120 to 135.
04 Nov 2025 Planned End Date changed from 1 Jan 2029 to 28 Feb 2030.
04 Nov 2025 Planned primary completion date changed from 1 Dec 2026 to 28 Feb 2028.

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