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Camrelizumab Plus Neoadjuvant Chemotherapy or Chemoradiotherapy Versus Neoadjuvant Chemoradiotherapy Alone for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma (NICE 2): a Multi-center, Randomized Phase II Trial

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Trial Profile

Camrelizumab Plus Neoadjuvant Chemotherapy or Chemoradiotherapy Versus Neoadjuvant Chemoradiotherapy Alone for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma (NICE 2): a Multi-center, Randomized Phase II Trial

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 22 Oct 2024

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At a glance

  • Drugs Camrelizumab (Primary) ; Carboplatin (Primary) ; Paclitaxel (Primary)
  • Indications Carcinoma; Oesophageal cancer; Squamous cell cancer; Thoracic neoplasms
  • Focus Therapeutic Use
  • Acronyms NICE-2 Study
  • Most Recent Events

    • 17 Oct 2024 Protocol has been amended to include changes in study phase, planned patients number and primary outcome.
    • 17 Oct 2024 Planned number of patients changed from 204 to 426.
    • 17 Oct 2024 Planned End Date changed from 6 Mar 2026 to 31 Dec 2030.

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