Trial Profile

A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 20 Jan 2026

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At a glance

Drugs Cabozantinib (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary)
Indications Brain metastases; Renal cell carcinoma
Focus Therapeutic Use

Most Recent Events

31 Dec 2025 Planned End Date changed from 31 Dec 2025 to 31 Jan 2027.
31 Dec 2025 Planned primary completion date changed from 31 Dec 2025 to 31 Jan 2027.
04 Sep 2025 Planned number of patients changed from 40 to 20.

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