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A Randomized, Observer-blind Trial to Assess the Immunogenicity and Safety of Third Dose Vaccination With AstraZeneca COVID-19 (ChAdOx1 AZD1222) Vaccine or Pfizer/BioNTech COVID-19 (BNT162b2) Vaccine Among Thai Adults Who Have Received Two Doses of Sinovac Inactivated COVID-19 Vaccine

Trial Profile

A Randomized, Observer-blind Trial to Assess the Immunogenicity and Safety of Third Dose Vaccination With AstraZeneca COVID-19 (ChAdOx1 AZD1222) Vaccine or Pfizer/BioNTech COVID-19 (BNT162b2) Vaccine Among Thai Adults Who Have Received Two Doses of Sinovac Inactivated COVID-19 Vaccine

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Apr 2023

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At a glance

  • Drugs AZD 1222 (Primary) ; Tozinameran (Primary)
  • Indications COVID 2019 infections
  • Focus Adverse reactions; Pharmacodynamics

Most Recent Events

  • 01 Apr 2023 Results comparing the immunogenicity and safety of fractional (half) third doses of heterologous COVID-19 vaccines (AZD1222 or BNT162b2) to full doses after the two-dose CoronaVac and when boosting after three different extended intervals, published in the International Journal of Infectious Diseases
  • 03 Jul 2022 Status changed from recruiting to completed.
  • 08 Apr 2022 Planned End Date changed from 1 Sep 2023 to 1 Sep 2024.

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