A Phase 1/2 Study of Avutometinib (VS-6766) in Combination With Sotorasib With or Without Defactinib in Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer (NSCLC)
Latest Information Update: 28 Dec 2024
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At a glance
- Drugs Avutometinib (Primary) ; Defactinib (Primary) ; Sotorasib (Primary)
- Indications Non-small cell lung cancer
- Focus Adverse reactions; Therapeutic Use
- Acronyms RAMP203
- Sponsors Verastem Oncology
- 18 Dec 2024 According to a Verastem Oncology media release, the Company plans to complete enrollment and evaluate the safety and efficacy of the triplet combination, before expanding either of the doublet cohorts.
- 18 Dec 2024 According to a Verastem Oncology media release, additional enrollment expected and an interim update is planned to be presented at a medical meeting in the second half of 2025.
- 18 Dec 2024 Results (As of a November 21, 2024) presented in the Verastem Oncology Media Release.