A Randomized, Multi-center, Double-blind, Placebo-controlled Phase 3 Study of Bemarituzumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer With FGFR2b Overexpression
Latest Information Update: 18 Dec 2025
At a glance
- Drugs Bemarituzumab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
- Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
- Focus Registrational; Therapeutic Use
- Acronyms FORTITUDE-101
- Sponsors Amgen
Most Recent Events
- 04 Nov 2025 According to an Amgen media release, in october, the full results from both the interim analysis and descriptive follow up analysis of the this clinical trial of bemarituzumab plus chemotherapy (mFOLFOX6) in first line gastric cancer were presented at ESMO.
- 23 Jul 2025 Planned End Date changed from 18 Aug 2025 to 20 Jun 2026.
- 30 Jun 2025 Interim results presented in an Amgen Media Release.