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A Phase I Study of Multiple Doses of Neural Stem Cell-Based Oncolytic Virotherapy (NSC-CRAd-S-pk7) Administered Intracerebrally to Patients With Recurrent High-Grade Gliomas

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Trial Profile

A Phase I Study of Multiple Doses of Neural Stem Cell-Based Oncolytic Virotherapy (NSC-CRAd-S-pk7) Administered Intracerebrally to Patients With Recurrent High-Grade Gliomas

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 23 Oct 2025

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At a glance

  • Drugs NeuroNova-1 (Primary)
  • Indications Astrocytoma; CNS cancer; Glioblastoma; Glioma; Oligodendroglioma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 03 Oct 2025 Efficacy primary end-point "Progression-free survival (PFS)" has been added.
  • 03 Oct 2025 Planned End Date changed from 7 Dec 2026 to 7 Aug 2026.
  • 03 Oct 2025 Planned primary completion date changed from 7 Dec 2026 to 7 Aug 2026.

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