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A Phase II Study of Cryoablation Combined With Sintilimab Plus Regorafenib in Previously Treated Colorectal Cancer Liver Metastasis (CASTLE-03)

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Trial Profile

A Phase II Study of Cryoablation Combined With Sintilimab Plus Regorafenib in Previously Treated Colorectal Cancer Liver Metastasis (CASTLE-03)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Mar 2025

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At a glance

  • Drugs Regorafenib (Primary) ; Sintilimab (Primary)
  • Indications Colorectal cancer; Liver metastases
  • Focus Therapeutic Use
  • Acronyms CASTLE-03

    • Most Recent Events

    • 25 Feb 2025 Planned End Date changed from 25 Sep 2024 to 25 Sep 2026.
    • 25 Feb 2025 Planned primary completion date changed from 25 Sep 2023 to 25 Sep 2026.
    • 30 Sep 2021 New trial record

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