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A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of Tarlatamab in Subjects With Relapsed/Refractory Small Cell Lung Cancer After Two or More Prior Lines of Treatment (DeLLphi-301).

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Trial Profile

A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of Tarlatamab in Subjects With Relapsed/Refractory Small Cell Lung Cancer After Two or More Prior Lines of Treatment (DeLLphi-301).

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Jan 2025

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At a glance

  • Drugs Tarlatamab (Primary)
  • Indications Small cell lung cancer
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Acronyms DeLLphi-301
  • Sponsors Amgen
  • Most Recent Events

    • 06 Jan 2025 According to an Amgen media release, announced that the UKs Medicines and Healthcare products Regulatory Agency (MHRA) has granted a conditional marketing authorization to IMDYLLTRA for the treatment of adult patients with extensive stage small cell lung cancer based on results from the Phase 2 open label, multicentre study DeLLphi-301.
    • 09 Sep 2024 Results (n=100) published in the Amgen Media Release.
    • 09 Sep 2024 According to an Amgen media release, the company announced the presentation of long-term results from the Phase 2 DeLLphi-301 study as an oral presentation at the 2024 World Conference on Lung Cancer (WCLC) in San Diego.

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