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A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of Tarlatamab in Subjects With Relapsed/Refractory Small Cell Lung Cancer After Two or More Prior Lines of Treatment (DeLLphi-301).

Trial Profile

A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of Tarlatamab in Subjects With Relapsed/Refractory Small Cell Lung Cancer After Two or More Prior Lines of Treatment (DeLLphi-301).

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 30 Jul 2026

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At a glance

  • Drugs Tarlatamab (Primary) ; Siltuximab
  • Indications Small cell lung cancer
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Acronyms DeLLphi-301
  • Sponsors Amgen

Most Recent Events

  • 22 Jul 2026 Planned primary completion date changed from 30 Dec 2026 to 30 Dec 2027.
  • 23 Jul 2025 Planned End Date changed from 31 Oct 2026 to 30 Apr 2027.
  • 23 Jul 2025 Planned primary completion date changed from 31 Oct 2025 to 30 Apr 2026.

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